Current Positions

Yunique Medical

2016 – Present

  • Founder & Chief Executive Officer
  • Creator of the YM Method®
  • Clinical locations: Ocala, Lady Lake (The Villages), and Port Orange, Florida
  • Founded 2016; clinical operations opened 2018

 

Global Provider Alliance

2020 – Present

  • Founder & Chief Executive Officer
  • International network of vetted physicians and pharmacies, developed to bridge international and U.S. providers and expand access to therapies otherwise unavailable domestically

Board Certification

Education

M.S.N., Nursing

B.S.N., Nursing

  • University of Florida, College of Nursing — 2001

Fellowship Training & Certifications

Clinical Fellow — Seeds Scientific Research & Performance (SSRP)

  • Institute dedicated to the study of cellular medicine and epigenetics

Fellow & Mastermind Member — International Peptide Society (IPS)

American Academy of Anti-Aging Medicine (A4M)

  • Certification in Functional Medicine
  • Certification in Hormone Therapy

Certified SottoPelle® Practitioner

  • Bio-identical hormone pellet therapy

Clinical & Professional Experience

Founder & Chief Executive Officer — Yunique Medical

2016 – Present

  • Built a three-location functional and longevity medicine practice serving Central Florida
  • Developed the YM Method®, an integrated protocol spanning hormone optimization, cellular and functional medicine, peptide therapy, and metabolic health
  • Expanded clinical services to include therapeutic plasma exchange, precision longevity programming, infusion and peptide therapy, regenerative orthopedics, and medically supervised weight optimization
  • Mentors nurse practitioners in clinical innovation and practice entrepreneurship

Founder & Chief Executive Officer — Global Provider Alliance

2020 – Present

  • Founded an international alliance connecting vetted physicians and pharmacies across borders
  • Developed supporting technology to facilitate provider collaboration and expand patient access to advanced therapies

Co-Founder & Chief Executive Officer — IVRx

2017 – 2018

  • Co-founded and led an intravenous nutrient and infusion therapy company

Co-Founder — Coastal Health & Wellness Centers

2015 – 2016

  • Co-founded a multi-site health and wellness therapy practice

Nurse Practitioner & Medical Advisory Board Member — Metabolic Research Centers

2009 – 2015

  • Developed and directed HCG and lipotropic weight management programs for a national weight-loss organization
  • Served on the company’s medical advisory board, contributing to clinical protocol design and program oversight

Nurse Practitioner — Family Care Specialists of Ocala

2008 – 2009

  • Full-scope urgent care and primary care practice

Registered Nurse, Critical Care

Munroe Regional Medical Center (now AdventHealth Ocala) and Ocala Regional Medical Center (now HCA Florida Ocala Hospital)
2001 – 2008

  • Eight years of intensive care nursing across Surgical (SICU), Medical (MICU), and Cardiovascular (CVICU) intensive care units

Clinical Research

Semaglutide’s Impact on Epigenetic Aging

Site Investigator

  • Longitudinal study investigating methylation changes occurring with semaglutide treatment, including effects on immune cell subsets, aging biomarkers, metabolite and protein biomarkers, and gene expression
  • Protocol incorporated advanced body composition testing, laboratory analysis, side-effect tracking, and quality-of-life measures, with the aim of informing a potential companion diagnostic
  • IRB: Tru-012-2022
  • Research Partner: TruDiagnostic
  • Status: Enrollment and data collection complete; publication pending

Speaking & Professional Education

Age Management Medicine Group (AMMG)

  • Invited speaker on peptide therapy (virtual presentation)

Clinical Peptide Society

  • Invited speaker on peptide therapy (virtual presentation)

Nurse Practitioner Mentorship

  • Ongoing mentorship of nurse practitioners in advanced clinical methods and practice development

Professional Memberships

Awards & Recognition

  • Gator100 — University of Florida — 2022, 2023, and 2024. Recognizing the 100 fastest-growing Gator-owned or Gator-led businesses in the world.
  • Inc. 5000 Regionals: Southeast — Ranked among the fastest-growing private companies in the Southeast.
  • Bronze Stevie® Award — The American Business Awards.
  • Gold Award — North Central Florida Media Group — 2024.
  • Community’s Choice Awards, Ocala — 2025 Winner.

Publications

  • Siegel L, et al. From Start to Success. Contributing author, featured alongside 39 other business leaders on entrepreneurship and professional development.
  • Siegel L. Stop the Hate! GLP-1 Agonists Are Not the Enemy! Meditech Today.
  • Siegel L. Value-based care services plant roots in the evolving healthcare landscape. Physicians Practice.

Media Features & Thought Leadership

  • USA Today — “Yunique Medical Brings Hospital-Grade Plasma Exchange to Underserved Florida Communities”
  • USA Today — “The Genuine Client Relationship Behind Yunique Medical’s Success”
  • Inc. — Feature on Yunique Medical’s culture, values, and results (CVR) framework
  • Authority Magazine — “Wellness Reimagined: Larry Siegel of Yunique Medical On 5 Things That Should Be Done To Improve and Reform The Health & Wellness Industry”
  • Authority Magazine — “Larry Siegel of Yunique Medical: Five Things You Need To Be A Highly Effective Leader During Turbulent Times”
  • University of Florida College of Nursing — Gator Nurse alumni features on Gator100 recognition (2022, 2023)
  • New York Weekly — “Yunique Medical: Redefining Healthcare with Larry Siegel’s Unique Vision”
  • Miami Weekly — “Experience Personalized Healing at Yunique Medical in Florida”
  • Additional syndicated features — on Yunique Medical’s approach to cellular and functional medicine, research and innovation, and the client wellness journey

Areas of Clinical Focus

  • Bio-identical hormone replacement therapy (BHRT) and hormone pellet therapy
  • Testosterone replacement therapy and male hormone optimization
  • Female hormone optimization and perimenopause/menopause management
  • Peptide therapy
  • Cellular and functional medicine
  • Therapeutic plasma exchange
  • Precision longevity and epigenetic age management
  • Metabolic health and medically supervised weight optimization (GLP-1 and GIP/GLP-1 therapies)
  • Nutritional IV and infusion therapy
  • Regenerative orthopedics

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