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Bioidentical Hormone Replacement Therapy

The Role Of Senescent Cells And Hormone Therapy

By December 21, 2020No Comments

As senescent cells accumulate with age, they churn out inflammatory proteins, causing tissue dysfunction and forcing neighboring cells into senescence. Many scholars who study aging now consider senescent cells as drivers of various age-related diseases and processes.

RELATED: How To Lengthen Telomeres Naturally and Age Better


Senescent Cell and Aging – What Is the Cure?

Why Senescence Is Important to Cellular Functioning?

Close up 3d concept of aging cells on red blackground - SS

When damaged cells are hurt beyond repair, a protective state called senescence will be triggered, preventing cells from dividing. The cell will also enter an automatic preprogrammed self-destruction – to prevent damaged or cancerous cells from proliferating, spreading to neighboring tissues in the body.

Senescence is crucial to cellular functioning. For instance, cancerous-mutated cells might enter senescence before dividing uncontrollably and form a tumor. Damaged cells caused by wounds can go senescent as well.

The physiological significance of senescence has been attributed to the prevention of:

  • Carcinogenesis
  • Tissue Repair
  • And most importantly, aging

Senescent Cells – Cells That Refuse Their Fate

Unfortunately, in some cases, damaged cells refuse their fate and turn themselves into zombie-like senescent cells. As people get older, senescent cells accumulate in greater amounts, causing harm to the neighboring cells and the entire body.

Senescence Can Drive Aging-Related Processes

The accumulation of senescent cells over time links to various aging-related processes:

  • Chronic Inflammation
  • Stem Cell Exhaustion
  • Mitochondrial Dysfunction in neighboring cells
  • Tissue Damage
  • Misfolded Proteins (associated with neurodegenerative disease)
  • Menopause (in women)


Definition: Menopause is the stage when hormones (in women) plunge drastically. Hormonal imbalance also occurs before, during, or after this phase, significantly affect the quality of life.

RELATED: Why Mitochondria Are So Important For Our Health

Natural Ways to Slow Down Senescence

Happy black senior couple smiling with each other - SS

While, according to many scientists, it’s not yet feasible to interrupt the process of senescence (some even argue that we will never be able to stop senescence), there are easy ways we can slow it down naturally:

  • Reducing Stress: to prevent over-exposure to the stress hormones and keep cortisol level under control.
  • Adopting a Healthy Eating Habit: to provide the body with essential nutrients for automatic repair from damage.
  • Exercising more often: to build strong tissues that are resistant to damage.
  • Avoiding Exposure to Toxic Substances: avoid over-exposure to UV lights, pollution, and toxins.

Fight Aging With Bioidentical Hormone Replacement Therapy (BHRT)

Besides selectively targeting and destroying senescent cells using senolytics, Bioidentical Hormone Replacement Therapy (BHRT) has also emerged as a promising therapeutic solution to age-related conditions.

Bioidentical Hormone Replacement Therapy (BHRT) is a plant-based therapy that mirrors hormone production, inserting various hormones with similar molecular structures to the hormones naturally secreted in the body.

BHRT can result in better skin, better sex, less anxiety, more restful sleep, and less tummy fat.

This therapy can help with hormonal issues in both men and women.

RELATED: How to Balance Hormones as You Age


Types of Bioidentical Hormone Replacement Therapy:

  • Hormone Creams
  • Hormone Injections
  • Hormone Pills
  • Hormone Pellets


Competitive Edges of Bioidentical Hormone Pellet Therapy

Hormone pellets are a great way to avoid the hormonal shock that other methods can cause. The pellets release hormones slowly and steadily, unlike a sudden surge of hormones after a pill or shot. Your body is free to determine the hormone absorption rate. If naturally, it takes three to six months for the pellets to dissolve.

Insertion of a hormone pellet is also much less invasive compared to other methods. Insertion is quick, painless, and doesn’t require stitches with potent pellets that are a bit bigger than a grain of rice.

Bioidentical hormone pellets can be customized to work with each patient’s unique body chemistry through a natural dosage during each treatment session. BHRT pellet therapy has not been associated with an increased risk of any adverse conditions or diseases.

Learn more about YM’s Bioidentical Hormone Pellet Therapy here.


The link between senescent cells and aging brings out an opportunity for science to move beyond addressing the aging symptoms and helps make a fundamental shift in the field of geriatric functional medicine. Bioidentical hormone replacement therapy, along with senolytics, comes as a beacon of hope amidst the ongoing war on aging!


Have Aging symptoms? Contact YM today and receive a FREE consultation session on Bioidentical Hormone Replacement Therapy, Performance Medicine, and Optimization at our Ocala, Florida, Fruitland Park, and Daytona offices!


GET STARTED 352.209.4249